Flyweight champion Alexandre Pantoja defends his title Saturday in the main event of UFC 301 against surging contender Steve Erceg. The main card is set for 10 p.m. ET from Farmasi Arena in Rio de Janeiro, Brazil.

Pantoja is a -190 favorite (risk $190 to win $100), while Erceg is priced at +160 (risk $100 to win $160) in the latest UFC 301 odds. Jonathan Martinez is the -160 favorite against Jose Aldo (+135) in the co-main event. 

Before making any UFC 301 picks, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani.

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In the last 10 UFC pay-per-view events, Vithlani has gone 7-3 on main-event picks and his main-card selections in that span have netted his followers a profit of more than $1,200. 

His highlights include calling an upset for Sean O'Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him is WAY UP!

This week at UFC 301, we can tell you Vithlani is backing Joaquim Silva (+135) to pull the mild upset of Drakkar Klose (-160) in a battle of lightweight veterans on the preliminary card.

Vithlani has strong picks for Pantoja vs. Erceg and other bouts on the UFC 301 card. He's also backing a fighter who "is younger and more dangerous" to emerge with a dominant victory! You ABSOLUTELY need to see his UFC 301 picks before making any of your own!

Who wins Pantoja vs. Erceg and which UFC 301 fighters are MUST-BACKS? Join SportsLine now to see which fighters you need to be all over Saturday, all from the expert  who has profited more than $1,200 on the last 10 UFC pay-per-view cards!